Oral function should be measured routinely to determine individual bulbar involvement stages in spinal muscular atrophy (SMA). “Our results underscore the heterogeneity of oral function effort across ...

"Decreasing AMMO [active maximal mouth opening] over time is seen most often in patients with SMA type 2 with an estimated reduction of almost 1 mm per year...At this point, we propose that ...

Noninvasive ventilation (NIV) is a well-established treatment for breathing difficulties caused by amyotrophic lateral sclerosis (ALS), even though its use has not been investigated in a randomized, ...

Patients with SMA often suffer from impaired bulbar function, which negatively affects quality of life and can be difficult to treat effectively. A German study prospectively followed children with ...

(RTTNews) - Novartis (NVS) announced new data that reinforce the transformational benefit of Zolgensma (onasemnogene abeparvovec), an essential one-time treatment for spinal muscular atrophy or SMA.

People with ALS now have more options to deal with a distressing set of symptoms called bulbar signs. These include difficulties with speech, swallowing, and salivation that result from ...