Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

Hypertrophic chondrocytes are deeply involved in the growth of mammalian bones. Researchers find that these cells transform ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous ...

A pair of proteins could contribute to the development of healthy, strong bones by directing early cell movement and blood vessel generation. A pair of proteins, YAP and TAZ, has been identified as ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...